Water treatment plants and water purifiers, a nest for super bacteria.

A recent article published by elDiario.es focuses on a problem that has been raising concern in specialized biomedical circles since some time ago. This is the increasing resistance of bacteria to antibiotics, and issue of great concern to our company Clover BioSoft. Although known for a long time, this problem has been alarmingly increasing since Leer másWater treatment plants and water purifiers, a nest for super bacteria.[…]

Detection of azole resistance in Aspergillus fumigatus complex isolates using MALDI-TOF mass spectrometry

Authors: Margarita Estreya Zvezdanova, Manuel J. Arroyo, Gema Méndez, Ana Candela, Luis Mancera, Julio García Rodríguez, Julia Lozano Serra, Rosa Jiménez, Inmaculada Lozano, Carmen Castro, Concepción López, Patricia Muñoz, Jesús Guinea, Pilar Escribano, and Belén Rodríguez-Sánchez on behalf of the ASPEIN group DOI: https://doi.org/10.1016/j.cmi.2021.06.005 The Aspergillus fumigatus complex is the main etiological agent of the Leer másDetection of azole resistance in Aspergillus fumigatus complex isolates using MALDI-TOF mass spectrometry[…]

An improved MALDI-TOF MS data analysis pipeline for the identification of carbapenemase-producing Klebsiella pneumoniae

Authors: Eva Gato, Ignacio Pedro Constanso, Ana Candela, Fátima Galán, Bruno Kotska Rodiño-Janeiro, Manuel J. Arroyo, Gema Méndez, Luis Mancera, Tyler Alioto, Marta Gut, Ivo Gut, Miguel Álvarez-Tejado, Belén Rodríguez-Sánchez, Germán Bou, Marina Oviaño DOI: 10.1128/JCM.00800-21 We present the latest published paper at JCM as a result of our collaboration with Microbiology Service from Hospital Leer másAn improved MALDI-TOF MS data analysis pipeline for the identification of carbapenemase-producing Klebsiella pneumoniae[…]

Implementation of MALDI-TOF Mass Spectrometry and Peak Analysis: Application to the Discrimination of Cryptococcus neoformans Species Complex and their Interspecies Hybrids

Author: Manuel J. Arroyo Pulgar Abstract: Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry (MALDI-TOF MS) has been widely implemented for the rapid identification of microorganisms. Although most bacteria, yeasts and filamentous fungi can be accurately identified with this method, some closely related species still represent a challenge for MALDI-TOF MS. In this study, two MALDI-TOF based Leer másImplementation of MALDI-TOF Mass Spectrometry and Peak Analysis: Application to the Discrimination of Cryptococcus neoformans Species Complex and their Interspecies Hybrids[…]

Initiatives to fight against antimicrobial resistance

Author: Verónica Sánchez Mercado As we know, antibiotics are medicines used to prevent and treat bacterial infections in humans and animals and resistance mechanisms occur when bacteria change in response to the use of these medicines. Antimicrobial resistance (AMR) is one of the biggest threats to global health. Nowadays, a growing number of infections are Leer másInitiatives to fight against antimicrobial resistance[…]

MALDI-TOF MS: A technology beyond bacterial analysis and biotyping

Author: Manuel J. Arroyo Pulgar At Clover Biosoft, we develop methods to identify and classify resistant microorganisms reducing time to result and cost of other methods and reagents. But our technology can go much beyond that. One of the advantages of mass spectrometry technology is its versatility, which can be used in many research fields, Leer másMALDI-TOF MS: A technology beyond bacterial analysis and biotyping[…]

New machine learning model leads to the discovery of powerful antibiotics

Author: Manuel J. Arroyo Pulgar Using a machine-learning algorithm, MIT researchers have identified a powerful new antibiotic compound. In laboratory preliminary test, the drug killed many of the world’s most problematic disease-causing bacteria, including Acinetobacter baumannii and Enterobacteriaceae. To understand the relevance of such discovery, these bacteria are two of three high-priority pathogens that the Leer másNew machine learning model leads to the discovery of powerful antibiotics[…]

The ESKAPE bacteria group and its clinical importance

Author: Manuel J. Arroyo Pulgar Health care-associated infections (HAIs) occur when receiving health care for another condition [1]. These infections can happen in any health-care facility and can be caused by any pathogen. A bigger problem in these HAIs is when the pathogen that caused the infection has an antibiotic resistance, something we talked about Leer másThe ESKAPE bacteria group and its clinical importance[…]

Alarming news in CDC’s 2019 Antibiotic Resistance Threats Report

Author: Manuel J. Arroyo Pulgar Centers for Disease Control and Prevention (CDC) just released the 2019 Antibiotic Resistance Threats Report in the United States. It includes statistics about infection due to resistant microorganisms in the U.S., an updated threats list about new antibiotic resistances and a lot of interesting complementary information about this worldwide problem, Leer másAlarming news in CDC’s 2019 Antibiotic Resistance Threats Report[…]

Health alert in Spain issued by Listeria monocytogenes

Authors: Manuel J. Arroyo Pulgar, Verónica Sánchez Mercado Listeriosis is an infection caused by a pathogenic bacterium called Listeria monocytogenes. Is one of the most virulent foodborne pathogens and in hight-risk individuals like pregnant women, older adults and people whose immune systems are compromised. In these population, the infection can be mortal and, in the Leer másHealth alert in Spain issued by Listeria monocytogenes[…]

es_ESES