MALDI-TOF MS: A technology beyond bacterial analysis and biotyping

Author: Manuel J. Arroyo Pulgar At Clover Biosoft, we develop methods to identify and classify resistant microorganisms reducing time to result and cost of other methods and reagents. But our technology can go much beyond that. One of the advantages of mass spectrometry technology is its versatility, which can be used in many research fields, Leer másMALDI-TOF MS: A technology beyond bacterial analysis and biotyping[…]

New machine learning model leads to the discovery of powerful antibiotics

Author: Manuel J. Arroyo Pulgar Using a machine-learning algorithm, MIT researchers have identified a powerful new antibiotic compound. In laboratory preliminary test, the drug killed many of the world’s most problematic disease-causing bacteria, including Acinetobacter baumannii and Enterobacteriaceae. To understand the relevance of such discovery, these bacteria are two of three high-priority pathogens that the Leer másNew machine learning model leads to the discovery of powerful antibiotics[…]

Clover Biosoft accesses tailor-made business opportunities with AB InBev

Author: Manuel J. Arroyo Pulgar On 19-20 February 2020, companies supported under the European Innovation Council (EIC) had the opportunity to accelerate their business collaborating with AB InBev, the world’s leading brewer and one of Europe’s biggest food and drinks companies. AB InBev opened its doors to 32 SMEs to pitch and present their business Leer másClover Biosoft accesses tailor-made business opportunities with AB InBev[…]

Bacteria characterization in ballast water using MALDI-TOF MS

Today, 22 March, is the World Water Day. It was created by the United Nations in 1993 to highlight the importance of fresh water, a resource that is not as reachable as it seems, unfortunately. It is essential for sustainable development and it plays a key role in poverty reduction, economic growth and the well-being Leer másBacteria characterization in ballast water using MALDI-TOF MS[…]

SEIMC Course special thanks

We would like to show our gratitude to SEIMC and specially to Dr. Belén Rodríguez from Hospital Gregorio Marañón of Madrid and Dr. Marina Ovianio from Hospital Universitario of A Coruña for the organization of the ‘First MALDI-TOF Applications Course in Clinical Microbiology’, where we imparted a seminar on data processing for MALDI-TOF MS and Leer másSEIMC Course special thanks[…]

Susceptibility testing with MALDI-TOF MS

Bacterial infections are one of the most common causes of death worldwide. That is why fast and correct therapies are a really important key for the survival of patients with such kind of diseases. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry entered the microbiological field some years ago, and since then, it has become an Leer másSusceptibility testing with MALDI-TOF MS[…]

Classification and identification of proteomic biomarkers with Machine Learning

Mass spectrometry technique is already known for its targeted, non-targeted and high throughput abilities that give it a great potential as a tool for proteomics data analysis. However, the quantification and identification methods that are used generate large amounts of data. At this point, a computational approach is required, and machine learning is one of Leer másClassification and identification of proteomic biomarkers with Machine Learning[…]

Catheter’s risk of resistant infections

The most common healthcare-acquired infections are urinary tract infections (UTIs), and half of them are associated with catheters. Approximately, a third of people catheterised develop bacteria in their urine after a few days, and 25% of them get infected. Fortunately, but still serious enough, a small percentage of them will develop life-threatening infections like sepsis. Leer másCatheter’s risk of resistant infections[…]

Antimicrobial resistance detection with MALDI-TOF MS

Application of MALDI-TOF MS to fight against bacterial resistance to antibiotics is growing fast. Traditional techniques are time-consuming and costly. This means the patient’s life is at risk. Therefore, it is important to find biomarkers of antimicrobial resistance to perform fast and cost-efficient resistance identification. MALDI-TOF MS has revolutionised pathogen identification. This has been described Leer másAntimicrobial resistance detection with MALDI-TOF MS[…]